Combination of a fixed design wave height with various wave periods may exert quite different wave loads on ocean structure. The response of structure induced by mild sea state may be larger than that by severe sea state because the frequency of the spectral peak for mild sea state is near to the natural frequency of structure. Thus it is necessary to investigate the worst combination between wave height and period, and also the critical combination between sea state and response for any design criteria. This paper presents a new combinative mode of wave height and period for equal return period. The selections of original design wave height and the critical combination of sea state with response for equal probability are also discussed.