Exposure to bifenthrin disrupts the development of testis in male <i>Sebastiscus marmoratus</i>

LI Jinshou; LUO Fen; LIU Liyue; RUAN Junfeng; WANG Nannan

doi:10.1007/s13131-017-1001-7

Volume 36 Issue 2

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Article Navigation > Acta Oceanologica Sinica > 2017 > 36(2): 57-61

LI Jinshou, LUO Fen, LIU Liyue, RUAN Junfeng, WANG Nannan. Exposure to bifenthrin disrupts the development of testis in male Sebastiscus marmoratus[J]. Acta Oceanologica Sinica, 2017, 36(2): 57-61. doi: 10.1007/s13131-017-1001-7

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LI Jinshou, LUO Fen, LIU Liyue, RUAN Junfeng, WANG Nannan. Exposure to bifenthrin disrupts the development of testis in male Sebastiscus marmoratus[J]. Acta Oceanologica Sinica, 2017, 36(2): 57-61. doi: 10.1007/s13131-017-1001-7

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Exposure to bifenthrin disrupts the development of testis in male Sebastiscus marmoratus

doi: 10.1007/s13131-017-1001-7

Department of Biology, Ningde Normal University, Ningde 352100, China

Received Date: 2016-08-22
Rev Recd Date: 2016-10-13

Abstract

Abstract

Bifenthrin (BF) is a pyrethroid insecticide that is widely used in agriculture, horticulture, and for residential purposes. However, few studies addressing the reproductive toxicity of BF on fishes are available. The present study was conducted to investigate the effects of BF on testicular development in Sebastiscus marmoratus and to gain insight into its mechanism. After exposure to 1, 10 and 100 ng/L BF for 50 days, there was a reduced number of mature sperm and an abundance of the late stages of spermatocysts in the testes. The levels of 17β-estradiol and testosterone were decreased significantly after BF exposure. The activity of caspase-3 was increased in a dose-dependent manner after BF exposure, TUNEL assay indicated that BF exposure resulted in the occurrence of apoptosis in the testes, which might be main reason for the inhibition of spermatogenesis.
- bifenthrin,
- apoptosis,
- reproductive toxicity,
- Sebastiscus marmoratus

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References

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