Exposure to bifenthrin disrupts the development of testis in male <i>Sebastiscus marmoratus</i>

LI Jinshou; LUO Fen; LIU Liyue; RUAN Junfeng; WANG Nannan

doi:10.1007/s13131-017-1001-7

Volume 36 Issue 2

Turn off MathJax

Article Contents

Abstract

References

Article Navigation > Acta Oceanologica Sinica > 2017 > 36(2): 57-61

LI Jinshou, LUO Fen, LIU Liyue, RUAN Junfeng, WANG Nannan. Exposure to bifenthrin disrupts the development of testis in male Sebastiscus marmoratus[J]. Acta Oceanologica Sinica, 2017, 36(2): 57-61. doi: 10.1007/s13131-017-1001-7

Citation:

LI Jinshou, LUO Fen, LIU Liyue, RUAN Junfeng, WANG Nannan. Exposure to bifenthrin disrupts the development of testis in male Sebastiscus marmoratus[J]. Acta Oceanologica Sinica, 2017, 36(2): 57-61. doi: 10.1007/s13131-017-1001-7

Citation:

PDF( 1849 KB)

Exposure to bifenthrin disrupts the development of testis in male Sebastiscus marmoratus

doi: 10.1007/s13131-017-1001-7

Department of Biology, Ningde Normal University, Ningde 352100, China

Received Date: 2016-08-22
Rev Recd Date: 2016-10-13

Abstract

Abstract

Bifenthrin (BF) is a pyrethroid insecticide that is widely used in agriculture, horticulture, and for residential purposes. However, few studies addressing the reproductive toxicity of BF on fishes are available. The present study was conducted to investigate the effects of BF on testicular development in Sebastiscus marmoratus and to gain insight into its mechanism. After exposure to 1, 10 and 100 ng/L BF for 50 days, there was a reduced number of mature sperm and an abundance of the late stages of spermatocysts in the testes. The levels of 17β-estradiol and testosterone were decreased significantly after BF exposure. The activity of caspase-3 was increased in a dose-dependent manner after BF exposure, TUNEL assay indicated that BF exposure resulted in the occurrence of apoptosis in the testes, which might be main reason for the inhibition of spermatogenesis.
- bifenthrin,
- apoptosis,
- reproductive toxicity,
- Sebastiscus marmoratus

FullText(HTML)

References(23)

References

Beggel S, Connon R, Werner I, et al. 2011. Changes in gene transcription and whole organism responses in larval fathead minnow (Pimephales promelas) following short-term exposure to the synthetic pyrethroid bifenthrin. Aquat Toxicol, 105(1-2):180-188

Borg B. 1994. Androgens in teleost fishes. Comp Biochem Physiol C-Pharmacol Toxicol Endocrinol, 109(3):219-245

Bradford M M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analyt Biochem, 72(1-2):248-254

Brander S M, He Guochun, Smalling K L, et al. 2012. The in vivoestrogenic and in vitro anti-estrogenic activity of permethrin and bifenthrin. Environ Toxicol Chem, 31(12):2848-2855

Callard G V, Tchoudakova A V, Kishida M, et al. 2001. Differential tissue distribution, developmental programming, estrogen regulation and promoter characteristics of cyp19 genes in teleost fish. J Steroid Biochem Mol Biol, 79(1-5):305-314

Cohen G M. 1997. Caspases:the executioners of apoptosis. Biochem J, 326(1):1-16

DeGroot B C, Brander S M. 2014. The role of P450 metabolism in the estrogenic activity of bifenthrin in fish. Aquat Toxicol, 156:17-20

Fenske M, Segner H. 2004. Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio). Aquat Toxicol, 67(2):105-126

Forsgren K L, Riar N, Schlenk D. 2013. The effects of the pyrethroid insecticide, bifenthrin, on steroid hormone levels and gonadal development of steelhead (Oncorhynchus mykiss) under hypersaline conditions. Gen Comp Endocrinol, 186:101-107

Harper H E, Pennington P L, Hoguet J, et al. 2008. Lethal and sublethal effects of the pyrethroid, bifenthrin, on grass shrimp (Palaemonetes pugio) and sheepshead minnow (Cyprinodon variegatus). J Environ Sci Health B, 43(6):476-483

Li Jinshou, Sun Lingbin, Zuo Zhenghong, et al. 2012. Exposure to paclobutrazol disrupts spermatogenesis in male Sebastiscus marmoratus. Aquat Toxicol, 122-123:120-124

Migliarini B, Campisi A M, Maradonna F, et al. 2005. Effects of cadmium exposure on testis apoptosis in the marine teleost Gobius niger. Gen Comp Endocrnol, 142(1-2):241-247

Miura T, Ohta T, Miura C I, et al. 2003. Yamauchi K. Complementary deoxyribonucleic acid cloning of spermatogonial stem cell renewal factor. Endocrinology, 144(12):5504-5510

Montanha F P, Galeb L A G, Mikos J D, et al. 2012. Pyrethroid toxicity in silver catfish, Rhamdia quelen. Pesq Veter Brasil, 32(12):1297-1303

Moore A, Waring C P. 2001. The effects of a synthetic pyrethroid pesticide on some aspects of reproduction in Atlantic salmon (Salmo salar L.). Aquat Toxicol, 52(1):1-12

Pennington P L, Harper-Laux H, Sapozhnikova Y, et al. 2014. Environmental effects and fate of the insecticide bifenthrin in a salt-marsh mesocosm. Chemosphere, 112:18-25

Pfaffl M W, Horgan G W, Dempfle L. 2002. Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res, 30(1):1-12

Schulz R W, de França L R, Lareyre J J, et al. 2010. Spermatogenesis in fish. Gen Comp Endocrinol, 165(3):390-411

Singh P B, Singh V. 2008. Cypermethrin induced histological changes in gonadotrophic cells, liver, gonads, plasma levels of estradiol-17β and 11-ketotestosterone, and sperm motility in Heteropneustes fossilis (Bloch). Chemosphere, 72(3):422-431

Srivastava R K, Yadav K K, Trivedi S P. 2008. Devicyprin induced gonadal impairment in a freshwater food fish, Channa punctatus (Bloch). J Environ Biol, 29(2):187-191

Sun Lingbin, Zuo Zhenghong, Luo Hongmin, et al. 2011. Chronic Exposure to Phenanthrene Influences the Spermatogenesis of Male Sebastiscus marmoratus:U-Shaped Effects and the Reason for Them. Environ Sci Technol, 45(23):10212-10218

Yılmaz M, Gül A, Erbaşlı K. 2004. Acute toxicity of alpha-cypermethrin to guppy (Poecilia reticulata, Pallas, 1859). Chemosphere, 56(4):381-385

Zheng S, Chen Bin, Qiu Xiaoyan, et al. 2016. Distribution and risk assessment of 82 pesticides in Jiulong River and estuary in South China. Chemosphere, 144:1177-1192

Relative Articles

Relative Articles

Supplements(0)

Cited By

Cited by

Periodical cited type(8)

1.	Jing Chang, Yifan Pan, Wentao Liu, et al. Lambda-cyhalothrin and its common metabolite differentially modulate thyroid disruption effects in Chinese lizards (Eremias argus). Environmental Pollution, 2021, 287: 117322. doi:10.1016/j.envpol.2021.117322
2.	PA Opute, IP Oboh, JE Asouzu, et al. Effects of atrazine on the endocrinology and histoarchitecture of the testes in African Catfish, Clarias gariepinus (Burchell, 1822). African Journal of Aquatic Science, 2021. doi:10.2989/16085914.2021.1890541
3.	Jing Chang, Yifan Pan, Lu Yang, et al. Environmental relevant concentration of λ-cyhalothrin and 3-phenoxybenzoic acid caused endocrine-disrupting effects on male lizards (Eremias argus). Environmental Pollution, 2020, 265: 115077. doi:10.1016/j.envpol.2020.115077
4.	Esra Akat. Characterization of testicular histology and spermatogenesis in the Levantine frog, Pelophylax bedriagae (Amphibia: Anura: Ranidae). Annales de Limnologie - International Journal of Limnology, 2020, 56: 19. doi:10.1051/limn/2020017
5.	Dandan Xiang, Linxi Zhong, Shuyuan Shen, et al. Chronic exposure to environmental levels of cis-bifenthrin: Enantioselectivity and reproductive effects on zebrafish (Danio rerio). Environmental Pollution, 2019, 251: 175. doi:10.1016/j.envpol.2019.04.089
6.	Sana Ullah, Zhongqiu Li, Amina Zuberi, et al. Biomarkers of pyrethroid toxicity in fish. Environmental Chemistry Letters, 2019, 17(2): 945. doi:10.1007/s10311-018-00852-y
7.	Xuefu Li, Jun Wang, Miao Yu, et al. 2, 2′-Dithiobis-pyridine induced reproductive toxicity in male guppy (Poecilia reticulata). Ecotoxicology and Environmental Safety, 2019, 169: 778. doi:10.1016/j.ecoenv.2018.11.076
8.	Ye Yang, Nanxiang Wu, Chunlei Wang. Toxicity of the pyrethroid bifenthrin insecticide. Environmental Chemistry Letters, 2018, 16(4): 1377. doi:10.1007/s10311-018-0765-0